Qualifi by Nextseq550 Standard USA

Qualifi Prenatal Test

What is Qualifi Test?

The Qualifi Test by NGG Thailand is prenatal cell-free fetal DNA screening for specific chromosomal abnormalities such as trisomy 21 (Down syndrome), 18 (Edwards syndrome), and 13 (Patau syndrome) without the risks associated with invasive procedures. This screening can also provide information about sex chromosome aneuploidies such as monosomy X (Turner syndrome) and XXY (Klinefelter syndrome) at no extra charge.

ตรวจคัดกรองดาวน์ซินโดรมทารกในครรภ์ Qualifi by Nextseq550

The Qualifi Test can be done as early as week 10 of pregnancy and test results are available within 5 days.

Who should be offered Qualifi?

  • The Qualifi Test is recommended for women at least 10 weeks gestational age who meets any of the following criteria:
  • Advanced maternal age (35 years or older)
  • Abnormal ultrasound findings associated with fetal chromosome abnormalities
  • Positive serum screening
  • Family history of chromosomal aneuploidies for trisomy 21, 18, 13, or sex chromosome aneuploidies

 

How is The Qualifi Test performed?

The genetic material from maternal blood sample (7-10 ml) is tested by Qualifi using the Massively Parallel Sequencing to count the number of copies of chromosomes, and then uses a calculation method to predict the risk of chromosomal aneuploidies for Trisomy 21, 18, 13, or sex chromosome aneuploidies presented in fetus. This screening test provides highly sensitive, accurate, and specific results with a very low possibility of false positive or false negative test. However, if a chromosome abnormality is identified, additional diagnostic testing, such as amniocentesis or CVS, is recommended to confirm the result.

 

What does Qualifi not test for?

The Qualifi Test is able to screen for the most common chromosome aneuploidies (Monosomy or trisomy of chromosomes 21, 18, 13 but it doesn’t screen for all chromosomes, genetic problems and microdeletions. The conditions involving in less effective of Qualifi Test are composed of multiple pregnancies (more than 2 babies), less than 10 weeks pregnant, and obese.
For more information about Qualifi, our tests or our services.

 

 

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